A historical perspective on the multifunctional outer membrane channel protein TolC in Escherichia coli
Authors: M Wright, M Kaur, L Thompson & G Cox (2025)
The inactivation of tolC sensitizes Escherichia coli to perturbations in lipopolysaccharide transport
Authors: S Zhu, MK Alexander, TO Paiva, K Rachwalski, A Miu, Y Xu, V Verma, M Reichelt, YF Dufrêne, ED Brown & G Cox (2024)
Autolysin-mediated peptidoglycan hydrolysis is required for the surface display of Staphylococcus aureus cell wall-anchored proteins
Authors: Leonard A, Goncheva M, Gilbert S, Shareefdeen H, Petrie L, Thompson L, Khursigara C, Heinrichs D & Cox G. (2023).
Proceedings of the National Academy of Sciences (PNAS)
Chinks in the Armor: Pathogenesis-Based Strategies to Combat Bacterial Infections
Authors: Leonard C, Stoica C & Cox G. (2022)
Pathogenesis of Bacterial Infections in Animals
Exploring functional interplay amongst Escherichia coli efflux pumps
Authors: Goetz J, Kuehfuss N, Botschner A, Zhu S, Thompson L & Cox G. (2022)
Microbiology
A genetic platform to investigate the functions of bacterial drug efflux pumps
Authors: Teelucksingh T, Thompson L, Zhu S, Kuehfuss N, Goetz J, Gilbert S, MacNair C, Geddes-McAlister J, Brown E & Cox G. (2022)
Nature Chemical Biology
Staphylococcus aureus adhesion to the host
Authors: Berry K, Verhoef M & Cox G. (2022).
Annals of the New York Academy of Sciences
Old Problems and New Solutions: Antibiotic Alternatives in Food Animal Production.
Authors: Stoica C & Cox G. (2021).
Canadian Journal of Microbiology. 99(999)
Development and validation of a high-throughput whole cell assay to investigate Staphylococcus aureus adhesion to host ligands
Authors: LE Petrie, AC Leonard, J Murphy & G Cox
Journal of Biological Chemistry
Resistance-guided discovery of elfamycin producers with antigonococcal activity.
Authors: V Yarlagadda, R Medina, TA Johnson, KP Koteva, G Cox, MN Thaker, GD Wright.
ACS Infectious Diseases
The Evolutionary Conservation of Escherichia coli Drug Efflux Pumps Supports Physiological Functions
Authors: T Teelucksingh, L Thompson & G Cox.
The Journal of Bacteriology
Antibiotic dereplication using the Antibiotic Resistance Platform
Authors: H Zubyk, G Cox & GD Wright
The Journal of Visualized Experiments
Bacterial anti-adhesives: inhibition of Staphylococcus aureus nasal colonization
Authors: A Leonard, L Petrie & G Cox
ACS Infectious Diseases
Plazomicin retains antibiotic activity against most aminoglycoside modifying enzymes
Authors: G Cox, L Ejim, PJ Stogios, K Koteva, E Bordeleau, E Evdokimova, AO Sieron, A Savchenko, AW. Serio, KM. Krause & GD Wright.
ACS Infectious Diseases
Substrate recognition by a colistin resistance enzyme from Moraxella catarrhalis
Authors: PJ Stogios, G Cox, HL Zubyk, E Evdokimova, Z Wawrzak, GD Wright & A Savchenko
ACS Chemical Biology
Rox, a rifamycin resistance enzyme with an unprecedented mechanism of action
Authors: K Koteva*, G Cox*, JK Kelso*, MD Surette, HL Zubyk, L Ejim, P Stogios, A Savchenko, D Sørensen & GD Wright.
Cell Chemical Biology
A common platform for antibiotic dereplication and adjuvant discovery
Authors: G Cox, AO Sieron, AM King, G DePascale, AC Pawlowski, K Koteva & GD Wright.
Cell Chemical Biology
The rifampin phosphotransferase is a new class of antibiotic resistance kinase
Authors: PJ Stogios*, G Cox*, P Spanogiannopoulos, MC Pillon, N Waglechner, T Skarina, K Koteva, A Guarné, A Savchenko & GD Wright.
Nature Communications
Structural and molecular basis for resistance to aminoglycoside antibiotics by the adenylyltransferase ANT(2”)-Ia
Authors: G Cox, PJ Stogios, A Savchenko & GD Wright.
mBio
Inhibition of the ANT(2’’)-Ia resistance enzyme and rescue of aminoglycoside antibiotic activity by synthetic a-hydroxytropolones
Authors: DR Hirsch*, G Cox*, MP D’Erasmo, T Shakya, C Meck, N Mohd, GD Wright & RP Murelli.
Bioorganic & Medicinal Chemistry Letters.